Dravet Syndrome is a genetic disorder of Chromosome 2 usually affecting a gene called SCN1A, causing epilepsy and other neurological and developmental problems. Dravet Syndrome accounts for 1% of the epilepsy population.
The condition gets its name from the doctor who first recognised and described it - Dr Charlotte Dravet.
Dr. Charlotte Dravet
How common is Dravet Syndrome?
of people with Dravet Syndrome have an SCN1A mutation. Of these, 95% have de novo mutations and 5% have inherited mutations. Mutations of SCN9A, SCN2B, PCDH19 and GABRG2 genes are also seen in Dravet Syndrome.
Who does it effect?
Can it be treated?
Why did it happen?
What Are The Features?
- Seizures starting in infancy
- Multiple seizure types
- Developmental delays emerging in early childhood
- Motor and behavioural disorders increasing with age
What are the Comorbidities?
- Autonomic dysfunction
- Autistic traits
- Attention deficit and hyperactivity
- Ataxia (unsteadiness)
- Orthopedic conditions
- Sleep disturbances
We would like to thank Dravet Syndrome UK for sharing this poster with us. We especially wish to thank Rebecca Dandy and Kate Watts, both Dravet parents, who created the infographic and added Canadian prevalence data so we can use this educational tool in Canada. This infographic was reviewed by Dr. Charlotte Dravet.